Liver transplant Liver transplantation is the replacement of a spoiled liver with some or all of a healthy liver from a healthy person. The most commonly used method is orthotopic transplantation, in which the diseased liver is taken out and exchanged by the donor organ in the same location. Liver transplantation is a feasible treatment option for the sufferer who is at the end of his life or acute liver failure. Typically three surgeons and two anesthesiologists are involved, with up to 4 supporting nurses. The surgical procedure is very demanding and ranges from 4 to 18 hours depending on the result. Numerous bring together and stitches, and many disparities and reconnections of abdominal and liver tissue must be made for the transplant to succeed. Liver replacement is possibly applicable to any intense or persistent condition resulting in long-term liver dysfunction, provided that the acceptor does not have other conditions that will avert a successful transplant. Precocious age and sober heart, lung or other diseases may also prevent transplantation. Most liver transplants are performed for a persistent liver illness that leads to irreversible damage of the liver.