Fillers & Injections Filler injections are a type of cosmetic treatment utilized to velvet wrinkles or cellular scars in the skin portion, that appears on the face. They also used to make the lips noteworthy. When injected nether the skin, a filler bumps up or heave that area. This usually goes away over time. There are numerous kinds of injectable fillers, including: Hyaluronic acid. The hyaluronic acid pulls off the fluid to the treated area. Bovine collagen (Zyplast, Zyderm). You have to take an allergy test 4 weeks before the start of treatment. Fat cells harvested from your body (autologous fat). Man-made biodegradable polymer (Sculptra). Microscopic plastic beads and bovine collagen (Artefill). Some doctors use fillers that are not approved by the U.S. Food and Drug Administration (FDA). Sit with your doctor and decide which treatment is right for you. For very few fillers, your skin is first blunt with a local anesthetic. Then a cosmetic surgeon uses a needle to inject the filler nether the skin. Some fillers are done in iterative sessions a couple of weeks apart.